Biochips Vena8 Fluoro+ Vena8 Endothelial+ VenaT4 Vena8 Glass Coverslip Low Flow Rates High Flow Rates Y1 Vena Delta Y2 Dimensions Channel width, b (cm): Channel height, h (cm): Channel length, L (cm): Channel volume (cm3): Channel volume (μL): Thickness of bottom substrate (mm) # of channels / chip # of assays / pack Pack of 5 Pack of 10 0.04 0.01 2.8 0.00112 1.12 0.17 8 40/80 CX-002 $ 768 CX-001 $ 1532 0.08 0.012 2.8 0.00269 2.69 0.5 8 40/80 CX-004 $ 768 CX-003 $ 1532 0.08 0.01 2.8 0.00224 2.24 0.16 0.016 2.8 0.00717 7.17 0.17 0.08 0.008 2.8 0.00179 1.79 0.17 8 80 0.008 0.012 2.8 0.00269 2.69 0.5 4 40 0.008 0.012 2.8 0.00269 2.69 0.5 4 40 4 40 8 80 PUMPS, MICROINJECTION CX-005 $ 1532 CX-009 $ 1532 CX-010 $ 1532 CX-007 $ 1532 CX-008 $ 1532 Specifications Brightfield, phase contrast & immunostaining Confocal microscopy Cell types: whole blood (human, animal); PRP; platelets; PBMC; monocytes; T-cells (primary & cell lines); eosinophils; neutrophils etc. Cell types: adherent cells e.g. endothelial – HUVECs; HMVECs etc.; HepG2; stem cells; muscle cells etc. Protein coatings: collagen, fibronectin, fibrinogen, vWF, VCAM, ICAM, selectins, MadCAM etc. ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ Applications Platelet adhesion, aggregation & thrombi formation; Leukocyte rolling, adhesion & migration; Thrombosis; Immunology (Inflammation); Infectious diseases (e.g. Malaria); Sickle cell disease; Respiratory (Asthma & COPD) Cell adhesion and culture under perfusion / shear flow; Leukocyte cell-cell rolling, adhesion & migration; Oncology (Melanoma, Breast Cancer etc.); Cardiovascular (Atherosclerosis, Drug eluting stents); Immunology (Inflammation); Respiratory (Asthma & COPD) Biofilm assays, microbe seeding & culturing; Biochips with glass coverslips (attached / not attached; treated / non-treated); Biochips for the attachment of coupons for biofilm studies Chemotaxis, transmigration and invasion assays; 2D and 3D cell culture; Mimicking tumour microenvironment with gels (ECM gel, hydrogel, matrigel, collagen gel) ✓ ✓ ✓ ✓ All biochips are: • Disposable plastic; some with glass coverslips. • Require no assembly; unlike many standard perfusion chambers / flow chambers. • Require no luer lock connections which increase dead volume. Cellix’s biochips have a unique plug & play connection with tubing connections which are autoclaveable and reuseable. UK: Tel: +44 (0)1462 424700 • wpiuk@wpi-europe.com World Precision Instruments www.wpiinc.com Germany: Tel: +49 (0)30-6188845 • wpide@wpi-europe.com US: Tel: 941-371-1003 • sales@wpiinc.com 183