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ISO-NOPF200-L10

ISO-NOPF200-L10

ISO-NOPF200-L10 Nitric Oxide Sensor - 200µm


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Overview

ISO-NOPF200-L10

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Instruction Manual
/ Download as PDF

  • For use with Apollo1000, Apollo4000, TBR4100 and TBR1025
  • Requires cable 91580 (sold separate)
  • Response Time: < 5 sec
  • Lowest Detection Limit: 0.2 nM
  • Sensitivity: 10 pA/nM
  • Application: in vivo
  • Flexible sensor, nearly unbreakable

L-Shaped sensor for tissue bath studies

The ISO-NOPF200-L10 is a unique L-shaped nitric oxide sensor designed specifically for use in tissue bath studies and similar applications (see WPI's MYOBATH ). The shape of the sensor has been engineered to facilitate placement of the electrode within the lumen of the tissue vessel under study. The ISO-NOPF200-L10 has a flexible tip (200 µm diameter).

 

Design

These sensors are based on a composite graphite NO-sensing element combined with a reference electrode. The surface of the sensor is then coated with a unique multi-layered NO-selective membrane.

Selectivity of WPI's NO sensors

The ideal NO sensor should be insensitive to other reactive species likely to be present within the measurement environment. Conventional Nafion coated carbon fiber NO sensor exhibits a large response to such species. WPI's unique NO sensor technology utilizes an novel surface membrane which amplifies the response to NO whilst eliminating responses to a vast range of reactive species, including nitrite, absorbic acid, hydrogen peroxide, catecolamines, and much more.

Specifications

Outside Diameter  200μm
Available Length    10mm
Response Time   < 5 seconds  
Lowest Detection Limit/Range 0.2nM
Nominal Sensitivity-New sensor   ≥50pA/nM 
Baseline Drift   none
Poise Voltage  865mV
Typical Quiescent Baseline Current, 25°C 3500pA
Acceptable Baseline Range   500-6000pA  
Polarization Time   8+ hours

 

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GlaxoSmithKline
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Novartis
Imperial College
University of Cambridge
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