ISO-NOP70-L
ISO-NOP70-L Nitric Oxide Sensor - 70 micron- Overview
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Overview
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Instruction Manual
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- For use with Apollo1000, Apollo4000, TBR4100 and TBR1025
- Requires cable 91580 (sold separate)
- Lowest Detection Limit: 1 nM
- Sensitivity: 10 pA/nM
- Application: Tissue Bath
- Package of 2
Details
L-Shaped sensor for tissue bath studies
The ISO-NOP70-L is a unique L-shaped nitric oxide sensor designed specifically for use in tissue bath studies and similar applications (e.g., see WPI's MYOBATH). The shape of the sensor has been engineered to facilitate placement of the electrode within the lumen of the tissue vessel under study. The ISO-NOP70-L has a flexible tip (70 µm diameter).
The response of a 7μm NO sensor (ISO-NOP007) to successive additions of NO (100nM). Inset shows the linearity of the resulting calibration plot.
Simultaneous measurement of force (top trace) and changes of NO concentration (lower trace) in (A) the rat superior mesenteric artery relaxed with ACh and (B) a small human artery relaxed with ACh and SNAP. In this artery oxyhaemoglobin (oxyHb) partly reversed the increase in NO concentration with only a small change in force. [U. Simonsen, et al., J. Physiol., 1999, 516: 271-282.]
Specifications
| Outside Diameter | 70μm |
| Available Length | 3mm |
| Response Time | < 3 seconds |
| Lowest Detection Limit/Range | 1nM |
| Nominal Sensitivity-New sensor | ≥1pA/nM |
| Baseline Drift | none |
| Poise Voltage | 865mV |
| Typical Quiescent Baseline Current, 25°C | 3500pA |
| Acceptable Baseline Range | 2000-6000pA |
| Polarization Time | 2+ hours |
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