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Home > Products > Biosensing > Free Radical Detection > TBR Biosensors > Nitric Oxide Detection > ISO-NOP3020

ISO-NOP3020

Nitric Oxide Sensor - 30um

Overview
Specifications
Accessories
Citations
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Overview

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Instruction Manual
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Requires cable 91580 (sold separate)
Response Time:
Lowest Detection Limit: 1 nM
Sensitivity: 1.4 pA/nM
Application: Microvessels

30 micron sensor with exceptional performance

The ISO-NOP30 has a tip diameter of 30 microns and is available in two different tip lengths (ISO-NOP3020 has tip length of 2 mm, ISO-NO3005 has tip length of 0.5 mm). The response is linear over a wide dynamic concentration range of NO. The design is based on a single carbon fiber coated with WPI's NO-selective membrane. A detection limit of approximately 1 nM NO makes these electrodes ideal for use in tissues and microvessels.

The response of a 7μm NO sensor (ISO-NOP007) to successive additions of NO (100nM). Inset shows the linearity of the resulting calibration plot.

Simultaneous measurement of force (top trace) and changes of NO concentration (lower trace) in (A) the rat superior mesenteric artery relaxed with ACh and (B) a small human artery relaxed with ACh and SNAP. In this artery oxyhaemoglobin (oxyHb) partly reversed the increase in NO concentration with only a small change in force. [U. Simonsen, et al., J. Physiol., 1999, 516: 271-282.]

Specifications

Outside Diameter	30μm
Available Length	2mm
Response Time	< 3 seconds
Lowest Detection Limit/Range	1nM
Nominal Sensitivity-New sensor	≥1.5pA/nM
Baseline Drift	none
Poise Voltage	865mV
Typical Quiescent Baseline Current, 25°C	500pA
Acceptable Baseline Range	500-5000pA
Polarization Time	1+ hours