Overview

The EVOM was the first instrument designed specifically to perform routine Trans Epithelial Electrical Resistance (TEER) measurement in tissue culture research. EVOM2 is the next generation, redesigned for ease of use. The EVOM2 not only qualitatively measures cell monolayer health, but also quantitatively measures cellular confluence. The unique electronic circuit of the EVOM2 and the included STX2 electrode detect the confluence of the cellular monolayer. When combined with WPI’s Endohm chamber, the EVOM2 can also be used to perform more accurate quantitative measurements or lower resistance measurements like trans endothelial electrical resistance measurements.

The isolated power source of the EVOM2 was specifically designed to avoid adverse effects on tissue and the formation of electrode metal deposits, even when it is plugged into a standard wall outlet. Now, the EVOM2 is always on when you need it. In addition, its rechargeable battery allows up to 10 hours of mobile use. The four and a half digit readout provides a range of 1-9,999 Ω. The included test electrode lets you calibrate the resistance measurements for an accurate reading every time, and the voltage meter never needs calibration. An analog BNC output is standard with the EVOM2, providing an output port for recording data or remote display of the EVOM2 output.

EVOM2 comes complete with the popular STX2 “chopstick” electrodes, 4 mm wide and 1mm thick. Each stick of the electrode pair contains a silver/silver-chloride pellet for measuring voltage and a silver electrode for passing current. The small size of each electrode is designed to facilitate placement of the electrodes into a variety of standard cell culture wells.

Other Resources

JOVE video: Models and Methods to Evaluate Transport of Drug Delivery Systems Across Cellular Barriers. J. Vis. Exp. (80), e50638, doi:10.3791/50638 (2013) can be watched here.

 

VIDEO: Models and Methods to Evaluate Transport of Drug Delivery Systems Across Cellular Barriers

See how to use and EndOhm chamber with an EVOM2 meter. 

In this video Mike shows you how to equilibrate your STX electrodes.

In this video, you can learn how to test your EVOM2.

Cellular Confluency of Epithelial Cells

The original EVOM was featured in this application video.

Specifications

Available models

Accessories

Citations

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