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Pulse Oximetry

Pulse oximetry is a non-invasive and painless test which measures oxygen saturation level.
It can rapidly detect even small changes in how efficiently oxygen is being carried to the extremities furthest from the heart, including the legs and the arms.

MouseOx® Plus Pulse Oximeter

World's first and only patented non-invasive vital signs monitor

for mice, rats, and other small laboratory animals.

M CollarClip™

CollarClip with Blank Clip

For use with Conscious Rodent, 31-100 gm

Benefits Of The MouseOx Plus Small Animal Pulse Oximeter

Arterial Saturation – The amount of oxygen bound to haemoglobin in mice, rats, and other small animals.
Heart Rate – Able to measure small animals with heart rates of 90 – 900 bpm.
Breath Rate – Provides breathing rate using the same sensor
Pulse Distension – Change in arteries at the Sensor site due to a heart beat
Breath Distension – Change in arteries at the sensor site sue to breathing
Temperature – Monitor subject core body temperature using the temperature probe
Activity – Monitoring gross motion of a subject over a period of time

	Heart Rates Of 90 – 900 BPM The MouseOx® Plus can be used on mice, rats and other small animals with a pulse rate of 90 – 900 bpm
	Noninvasively Measure Up To 7 Parameters Measure up to 7 physiological parameters without invasive surgical procedures
	Anesthetized & Conscious Subjects Special sensors and software modules allow you to monitor both anesthetized & conscious subjects.
	Non-Magnetic MRI Compatible Monitor your subject’s health during MRI imaging using the Non-Magnetic MRI Sensor
	Monitor Up To 16 Individuals Utilizing a Multiplexer, you can sequentially monitor up to 16 individuals one-at-a-time, using one MouseOx® Plus.
	Analogue Output Of Pulse Waveform Outputs the raw pulse waveform for input into other data acquisition systems

Selecting A MouseOx Plus Small Animal Pulse Oximeter

MouseOx Plus

The MouseOx Plus (MOX-INT-120V/240V) package comes with the MouseOx Plus control unit, basic monitoring software and two sensors of your choice (excludes custom, non-magnetic and temperature sensors). Features include:

MouseOx Plus Standard Features
Software*	Parameters Arterial Saturation (SpO2) Heart Rate Breath Rate Pulse Distension Breath Distension
	Vital Signs Numeric Summary
	Anesthesia Alarms
Hardware	Analogue Pulse Signal Output

*See accessories section for module upgrades to enhance the software including adding the ability to record data, measure temperature and work with awake animals.

MouseOx has a wide range of accessories available to enhance your ability to make measurements in many different environments and conditions.

MouseOx Plus Sensors

MouseOx Plus sensors have a service life of 100 hours to maintain measurement quality. An alert is displayed within the software to confirm the remaining service life of a sensor. The measurement will not be interrupted in the middle of an experiment.


Mouse Thigh Sensor The Mouse Thigh Sensor is used with the MouseOx Plus for obtaining vital sign measurements from an anesthetized mice by providing a strong signal from femoral artery.	Mouse Paw Sensor The Mouse Paw Sensor is used for obtaining vital sign measurements from the paw of anesthetized mice. The sensor can be used to obtain measurements from a mouse tail.	Rat Foot Sensor The Rat Foot Sensor is used with the MouseOx Plus for obtaining vital sign measurements from an anesthetized rat’s foot.	Throat Sensor The Throat Sensor is used with the MouseOx Plus for obtaining vital sign measurements from an anesthetized animal in the supine position by obtaining a strong signal from the carotid arteries.

Collar Sensor The Collar Sensor is used with the MouseOx Plus for obtaining vital sign measurements from a Concious or Anesthetized animal in the prone position by obtaining a strong signal from the carotid arteries. The Collar type sensor comes with a blank clip to facilitate hair removal around the neck and to accustom the animal to the clip before measurement.	Non-Magnetic MRI Compatible Sensor The Non-Magnetic MRI Compatible Sensor is for anesthetized subjects and can be used in small, large and closed bore MRI environments up to 19T. The MRI Compatible Sensor can also be used in conjunction with MouseOx Plus Temperature Sensor.	Rectal Temperature Sensor The MouseOx Plus can measure Mouse or Rat core body temperature with the addition of the Rectal Temperature Sensor and included Temperature Software.

Description	Part Number
Mouse Thigh Sensor
Thigh Sensor: Anesthetized Mouse < 60 g; Rat <= 100 g	MOX-SNSR-MTHGH
Mouse Paw Sensor
Mouse Paw Sensor	MOX-SNSR-MPAW
Rat Foot Sensor
Rat Foot Sensor: Anesthetized Rat > 100g	MOX-SNSR-RTFT
Throat Sensor
XS ThroatClip: Anesthetized Unshaved Mouse 1-15 g, Shaved Mouse 1 - 20 g	MOX-SNSR-THRT-XS
S ThroatClip: Anesthetized Unshaved Mouse > 15 g, All Mice > 20 g; Rat 5 - 30 g	MOX-SNSR-THRT-S
M ThroatClip : Anesthetized Rat 31 - 100 g	MOX-SNSR-THRT-M
L ThroatClip: Anesthetized Rat 101 - 300 g	MOX-SNSR-THRT-L
XL ThroatClip: Anesthetized Rat 301 - 500 g	MOX-SNSR-THRT-XL
2XL ThroatClip: Anesthetized Rat > 500 g	MOX-SNSR-THRT-2XL
Collar Sensor
XS CollarClip w/ Blank Clip: Conscious Unshaved Mouse 1 - 15 g, Shaved Mouse 1 - 20 g	MOX-SNSR-CLLR-XS
S CollarClip w/ Blank Clip: Conscious Unshaved Mouse > 15 g, All Mice > 20 g, Rat 5 - 30 g	MOX-SNSR-CLLR-S
M CollarClip w/ Blank Clip: Conscious Rat 31 - 100 g	MOX-SNSR-CLLR-M
L CollarClip w/ Blank Clip: Conscious Rat 101 - 300 g	MOX-SNSR-CLLR-L
XL CollarClip w/ Blank Clip: Conscious Rat 301 - 500 g	MOX-SNSR-CLLR-XL
2XL CollarClip w/ Blank Clip: Conscious Rat > 500 g	MOX-SNSR-CLLR-2XL
Non-Magnetic MRI Compatible Sensor
Thigh Sensor, Non-Magnetic Spring	MOX-SNSR-MTHGH-NM
Rat Foot Sensor, Non-Magnetic Spring	MOX-SNSR-RTFT-NM
Rectal Temperature Sensor
2m Temperature Sensor, Sensor Only	MOX-SNSR-TEMP-2M
4m Temperature Sensor, Sensor Only	MOX-SNSR-TEMP-4M
7m Temperature Sensor, Sensor Only	MOX-SNSR-TEMP-7M

MouseOx Plus Accessories

Accessory
Premium Monitoring Software Added functionality of software: Vital Sign Real-Time Trends Temperature and MRI monitoring (purchase of respective sensors required) Scheduling Software Diagnostic Averaging With Recording For Spot-Checking File Recording And Event Marking High speed data acquisition/recording (.tdms format) Continuous “streaming” parametric data (15 Hz) Continuous discrete data sampling (Snapshot) – user specified Cardiac PhotoPlethysmogram Recording (300 Hz) Export all or parts of data files to “.tdms” or “.csv” formats for use with 3rd-party analysis software Part Numbers Premium Monitoring Software (MOX-SFTWMOD-REC)
Body Temperature Option The MouseOx Plus Temperature Probe can be used to measure the core body temperature of a small animal or to monitor ambient temperature during experimental procedures. The sensor probe is made of implant grade titanium and is MRI compatible. Available in 2m, 4m and 7m lengths. Part Numbers Requires Premium Monitoring Software (MOX-SFTWMOD-REC) and a Rectal Temperature Sensor Rectal temperature probe with 2m cable (MOX-SNSR-TEMP-2M) Rectal temperature probe with 4m cable (MOX-SNSR-TEMP-4M) Rectal temperature probe with 7m cable - recommended for MRI (MOX-SNSR-TEMP-7M)
Conscious Subjects Software The Conscious Applications Software includes enhanced filters and control algorithms which optimize the MouseOx® Plus for use on conscious, moving subjects. (purchase of respective sensors required) Part Numbers Requires Conscious Subjects Software (MOX-SFTWMOD-CON) and Premium Monitoring Software (MOX-SFTWMOD-REC) and sensor(s) For Conscious Subjects XS CollarClip™ w/ Blank Clip: Conscious Unshaved Mouse 1-15 gm, Shaved Mouse 1-20 gm (MOX-SNSR-CLLR-XS) S CollarClip™ w/ Blank Clip: Conscious Unshaved Mouse > 15 gm, All Mice > 20 gm, Rat 5-30 gm (MOX-SNSR-CLLR-S) M CollarClip™ w/ Blank Clip: Conscious Rat 31-100 gm (MOX-SNSR-CLLR-M) L CollarClip™ w/ Blank Clip: Conscious Rat 101 - 300 gm (MOX-SNSR-CLLR-L) XL CollarClip™ w/ Blank Clip: Conscious Rat 301 - 500 gm (MOX-SNSR-CLLR-XL) 2XL CollarClip™ w/ Blank Clip: Conscious Rat >500 gm (MOX-SNSR-CLLR-2XL)
Conscious Measurement Enclosure (CME) Animal holding chambers for conscious measurements – rat and mouse sizes Part Numbers Conscious Measurement Enclosure Conscious Measurement Enclosure for Mice (MOX-STCME-M) Conscious Measurement Enclosure for Rats (MOX-STCME-R)
MRI Compatible Oximeter Sensors The Non-Magnetic MRI Compatible Sensor is for anesthetized subjects and can be used in small, large and closed bore MRI environments up to 19T. The MRI Compatible Sensor can also be used in conjunction with MouseOx Plus Temperature Sensor. Part Numbers Sensors compatible for MRI Thigh Sensor, Non-Magnetic Spring (MOX-SNSR-MTHGH-NM) Rat Foot Sensor, Non-Magnetic Spring (MOX-SNSR-RTFT-NM) Rectal temperature probe with 7m cable - recommended for MRI* (MOX-SNSR-TEMP-7M) Contact WPI for other non-magnetic size options.
Analogue Data Output The STARR-Link Analogue Output Module provides 0-5 V analogue outputs of the parameters (IR/PPG raw cardiac waveform) measured by the MouseOx Plus. It serves as an interface between the MouseOx Plus and other data acquisition hardware. This module is primarily used for event triggering, Part Numbers STARR-Link Plus, Analogue Data Output Module (MOX-AOM)
Multiplexer The Multiplexer is a sensor Switching Unit for MouseOx Plus that allows a single MouseOx Plus to monitor and record data from up to 16 subjects. The Multiplexer allows you to choose between automatic, scheduled, or manual switching. Part Numbers Select between 3 multiplexer options 8 Channel Multiplexer allows you to monitor and record data from up to 8 subjects, using one MouseOx Plus control unit (MOX-MUX8-230V) 8 Channel Multiplexer with Temperature allows you to monitor and record data from up to 8 subjects, using one MouseOx Plus control unit (MOX-MUX8X8-230V)* 16 Channel Multiplexer allows you to monitor and record data from up to 16 subjects, using one MouseOx Plus control unit (MOX-MUX16-230V)

Accessory

Premium Monitoring Software

Added functionality of software:

Vital Sign Real-Time Trends
Temperature and MRI monitoring (purchase of respective sensors required)
Scheduling Software
Diagnostic Averaging With Recording For Spot-Checking
File Recording And Event Marking
High speed data acquisition/recording (.tdms format)
Continuous “streaming” parametric data (15 Hz)
Continuous discrete data sampling (Snapshot) – user specified
Cardiac PhotoPlethysmogram Recording (300 Hz)
Export all or parts of data files to “.tdms” or “.csv” formats for use with 3rd-party analysis software

Part Numbers

Premium Monitoring Software (MOX-SFTWMOD-REC)

Body Temperature Option

The MouseOx Plus Temperature Probe can be used to measure the core body temperature of a small animal or to monitor ambient temperature during experimental procedures. The sensor probe is made of implant grade titanium and is MRI compatible. Available in 2m, 4m and 7m lengths.

Part Numbers

Requires Premium Monitoring Software (MOX-SFTWMOD-REC) and a Rectal Temperature Sensor

Rectal temperature probe with 2m cable (MOX-SNSR-TEMP-2M)
Rectal temperature probe with 4m cable (MOX-SNSR-TEMP-4M)
Rectal temperature probe with 7m cable - recommended for MRI (MOX-SNSR-TEMP-7M)

Conscious Subjects Software

The Conscious Applications Software includes enhanced filters and control algorithms which optimize the MouseOx® Plus for use on conscious, moving subjects. (purchase of respective sensors required)

Part Numbers

Requires Conscious Subjects Software (MOX-SFTWMOD-CON) and Premium Monitoring Software (MOX-SFTWMOD-REC) and sensor(s) For Conscious Subjects

XS CollarClip™ w/ Blank Clip: Conscious Unshaved Mouse 1-15 gm, Shaved Mouse 1-20 gm (MOX-SNSR-CLLR-XS)
S CollarClip™ w/ Blank Clip: Conscious Unshaved Mouse > 15 gm, All Mice > 20 gm, Rat 5-30 gm (MOX-SNSR-CLLR-S)
M CollarClip™ w/ Blank Clip: Conscious Rat 31-100 gm (MOX-SNSR-CLLR-M)
L CollarClip™ w/ Blank Clip: Conscious Rat 101 - 300 gm (MOX-SNSR-CLLR-L)
XL CollarClip™ w/ Blank Clip: Conscious Rat 301 - 500 gm (MOX-SNSR-CLLR-XL)
2XL CollarClip™ w/ Blank Clip: Conscious Rat >500 gm (MOX-SNSR-CLLR-2XL)

Conscious Measurement Enclosure (CME)

Animal holding chambers for conscious measurements – rat and mouse sizes

Part Numbers

Conscious Measurement Enclosure

Conscious Measurement Enclosure for Mice (MOX-STCME-M)
Conscious Measurement Enclosure for Rats (MOX-STCME-R)

MRI Compatible Oximeter Sensors

The Non-Magnetic MRI Compatible Sensor is for anesthetized subjects and can be used in small, large and closed bore MRI environments up to 19T. The MRI Compatible Sensor can also be used in conjunction with MouseOx Plus Temperature Sensor.

Part Numbers

Sensors compatible for MRI

Thigh Sensor, Non-Magnetic Spring (MOX-SNSR-MTHGH-NM)
Rat Foot Sensor, Non-Magnetic Spring (MOX-SNSR-RTFT-NM)
Rectal temperature probe with 7m cable - recommended for MRI* (MOX-SNSR-TEMP-7M)

Contact WPI for other non-magnetic size options.

Analogue Data Output

The STARR-Link Analogue Output Module provides 0-5 V analogue outputs of the parameters (IR/PPG raw cardiac waveform) measured by the MouseOx Plus. It serves as an interface between the MouseOx Plus and other data acquisition hardware.

This module is primarily used for event triggering,

Part Numbers

STARR-Link Plus, Analogue Data Output Module (MOX-AOM)

Multiplexer

The Multiplexer is a sensor Switching Unit for MouseOx Plus that allows a single MouseOx Plus to monitor and record data from up to 16 subjects. The Multiplexer allows you to choose between automatic, scheduled, or manual switching.

Part Numbers

Select between 3 multiplexer options

8 Channel Multiplexer allows you to monitor and record data from up to 8 subjects, using one MouseOx Plus control unit (MOX-MUX8-230V)
8 Channel Multiplexer with Temperature allows you to monitor and record data from up to 8 subjects, using one MouseOx Plus control unit (MOX-MUX8X8-230V)*
16 Channel Multiplexer allows you to monitor and record data from up to 16 subjects, using one MouseOx Plus control unit (MOX-MUX16-230V)

* Requires Premium Monitoring Software

MOX-INT-120V/240V

MouseOxPlus 230VAC (old part number 015001)

Includes MouseOx Plus control box ...

View details...

MOX-SFTWMOD-REC

MouseOxPlus® Recording Module, Product Key (old part number 015007).

The Premium Software includes trending charts, real time recording options, file markers for noting important events, and a quick averaging diagnostic feature for spot-checking.

MOX-SFTWMOD-CON

MouseOxPlus® Conscious Applications Module, Product Key (old part number 015002)

MOX-MUX16-230V

16 Channel Multiplexer, 230V (old part number 015016)

Monitor & Record data of up to 16 Subjects with a MouseOx Plus
Retain the control that you need with automatic, scheduled, and manual switching options
The Summary Screen shows data from all subjects being monitored through the Multiplexer

The Multiplexer 16 allows you to monitor and record the data of up to 16 subjects from a single MouseOx Plus control when using the Premium Monitoring Software Module.

MOX-MUX8-230V

8 Channel Multiplexer, 230V (old part number 015039)

Monitor & Record data of up to 8 Subjects with a MouseOx Plus
Retain the control that you need with automatic, scheduled, and manual switching options
The Summary Screen shows data from all subjects being monitored through the Multiplexer

The Multiplexer 8 allows you to monitor and record the data of up to 8 subjects from a single MouseOx Plus control when using the Premium Monitoring Software Module.

MOX-MUX8X8-230V

8 Channel Multiplexer with Temperature, 230V (old part number 015041)

Monitor & Record data, including temperature of up to 8 Subjects with a MouseOx Plus
Retain the control that you need with automatic, scheduled, and manual switching options
The Summary Screen shows data from all subjects being monitored through the Multiplexer

The Multiplexer 8 with Temperature allows you to monitor and record the data, including temperature, of up to 8 subjects from a single MouseOx Plus control when using the Temperature probe and Premium Monitoring Software Module.