MIRUS-EVO-PRO
The Mirus™ Evo Nanopump is a microfluidic syringe pump PC controlled via VenaFluxAssay Software.- Overview
- Specifications
- Accessories
- Citations
- Related Products
Overview
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Quick Start - MIRUS Washout
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Quick Start - MIRUS Connect Tubing
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Quick Start - VenaFlux Assay
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Features:
- Includes MultiFlow8 for precision flow splitting with equal flow rate in each channel.
- MultiFlow8 contains 8 valves which can be switched on/offi independently.
- Higher throughput enabling 8 assays in parallel.
- Patented flow damper to decrease syringe pump pulses - particularly important when connecting to microfluidic biochips to prevent pusling/jerking motion comapred to standard syringe pump.
- Flow rate: 100nL/min - 10mL/min ± 1%.
- Standard syringes: 50µL - 5mL.
- Dead volume: ~600µL.
- Flow direction reversible.
- PC controlled via VenaFluxAssay software.
- Mirus Evo may be sold separately without MultiFlow8. MultiFlow8 can be purchased later if required.
- Includes tubing kit for Vena8 biochips or alternative tubing kits for connection to any microfluidic biochip.
Applications: Microfluidic applications, single cell analysis, Microfluidic syringe pump for cell analysis under shear flow in biochips. Suitable for cell samples and whole blood samples.
Specifications
MultiFlow8TM |
Capable of executing up to 8 assays in parallel in Vena8TM biochips resulting in an 8-channel syringe pump. |
Shear Stress Range for cell suspension |
0.05 - 10 dyne/cm2; steps of 0.05 dyne/cm2 (100 mL syringe) |
Shear Stress Range for whole blood* |
2.25 - 450 dyne/cm2 (1 mL syringe) |
Volumetric Flow Rates |
100 nL/minute - 20 μL/minute (100 mL syringe) |
Dead Volume |
600 μL |
Sample Volume Increments |
|
Valve Switching Time |
30 ms max (at 20°C, 2Hz, with air under 10psi pressure) |
Working Pressure |
30 psi – 2 bars maximum |
Linear Velocity Range** |
10 μm/s to 10 cm/s |
Flow Direction |
Reversible |
Sample Volume Aspiration Accuracy |
±1% |
Shear Stress Accuracy |
±0.5% |
Sample Volume Aspiration Precision |
|
Shear Stress Precision |
|
External Trigger |
2 inputs and 2 outputs external trigger for better operation with external units and softwares |
Software Control |
Integrated VenaFlux Assay software |
Dimensions |
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Weight |
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Citations
Aelst, B. Van, & Devloo, R. (2015). Ultraviolet C light pathogen inactivation treatment of platelet concentrates preserves integrin activation but affects thrombus formation kinetics on collagen in vitro. …. Retrieved from https://onlinelibrary.wiley.com/doi/10.1111/trf.13137/full
Calmer, S., Ferkau, A., Larmann, J., & Johanning, K. (2014). Desmopressin (DDAVP) improves recruitment of activated platelets to collagen but simultaneously increases platelet endothelial interactions in vitro. Platelets. Retrieved from https://www.tandfonline.com/doi/abs/10.3109/09537104.2013.767442#
Curcic, S., Holzer, M., Frei, R., & Pasterk, L. (2015). Neutrophil effector responses are suppressed by secretory phospholipase A 2 modified HDL. … et Biophysica Acta (BBA …. Retrieved from https://www.sciencedirect.com/science/article/pii/S1388198114002492
Dominical, V., Vital, D., & O’Dowd, F. (2015). In vitro microfluidic model for the study of vaso-occlusive processes. Experimental …. Retrieved from https://www.sciencedirect.com/science/article/pii/S0301472X14007504
Kashanin, D., Shvets, I., Williams, V., & O’dowd, F. (2014). Method for measuring the migration of cells in a channel under the influence of an analyte. US Patent 8,802,391. Retrieved from https://www.google.com/patents/US8802391
Konya, V., Peinhaupt, M., & Heinemann, A. (2014). Adhesion of Eosinophils to Endothelial Cells or Substrates Under Flow Conditions. Eosinophils. Retrieved from https://link.springer.com/protocol/10.1007/978-1-4939-1016-8_13
Natoni, A., Moschetta, M., Glavey, S., & Wu, P. (2014). Multiple Myeloma Cells Express Functional E-Selectin Ligands Which Can be Inhibited Both in-Vitro and in-Vivo Leading to Prolongation of Survival in a. Blood. Retrieved from https://www.bloodjournal.org/content/124/21/4718.abstract
Salles-Crawley, I., Monkman, J., & Ahnström, J. (2014). Vessel wall BAMBI contributes to hemostasis and thrombus stability. Blood. Retrieved from https://www.bloodjournal.org/content/123/18/2873.short
Shaker, M., Colella, L., Caselli, F., Bisegna, P., & Renaud, P. (2014). An impedance-based flow microcytometer for single cell morphology discrimination. Lab on a Chip. Retrieved from https://pubs.rsc.org/en/content/articlehtml/2014/lc/c4lc00221k
Tischer, A., & Madde, P. (2014). A molten globule intermediate of the von Willebrand factor A1 domain firmly tethers platelets under shear flow. Proteins: Structure, …. Retrieved from https://onlinelibrary.wiley.com/doi/10.1002/prot.24464/full
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