RFLSI III Laser Speckle Contrast Imaging System
The RFLSI III Laser Speckle Imaging System is a blood perfusion imager based on the latest Laser Speckle Contrast Imaging (LSCI) technology. It offers real-time dynamic blood flow monitoring and video imaging via unique non-contact, high time and spatial resolution. As the RFLSI III is contactless there is no influence on the perfusion and no dyes or tracer elements are required.
- Overview
- Specifications
- Accessories
- Citations
- Related Products
Overview
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Applications:
- Cerebral blood flow, MCAO model
- Cortical Spreading Depression (CSD)
- Hind/Critica Limb Ischaemia (HLI)/(CLI)
- Neuro-Vascular Coupling
- Burn Assessment, Traumatic Brain Injury(TBI) and Sepsis
Overview
The RFLSI III can be used to measure the microcirculation of any exposed superficial vessels, such as the cortex, mesentery, lower limbs, and spinal cord. It is a popular choice and has been used in more than 100 colleges, universities, and research institutes throughout the world. It offers:
- Non-invasive, real-time, full-field imaging with high-definition; no need for scanning, no need of contact, no need of contrast for imaging
- 12x Optical lens, autofocus, electrical zoom, allows researchers to adjust the image area as they need
- Built-in Basler camera delivering high definition and high speed imaging. Image resolution up to 2048 x 2048 pixels and high frame rate speed of up to 120 frames per second
- Dual 3.0 USB interface for fast data transmission, high frame rate and high resolution
- A Thorlabs laser is used to output laser with good coherence to ensure the stability of baseline data and obtain the fluctuation data of real blood perfusion
- Blood flowmeter (the volume of blood perfusion expressed as conventional unit PU) to observe the relative changes in the velocity of blood flow by combining image data with perfusion data
- The global PU value is adopted to quantify the values of blood perfusion and obtain the objective data changes in the velocity of blood flow.
- Combining the image data and perfusion data, the velocity of blood flow can be observed by the pictures, and the relative velocity of blood flow can be judged by different colors. (Perfusion Unit)
- Hardware structures including instruction laser and Cardan gimbals and humanized software operation mode make the whole system easy to use
Specifications
| RFLSI III | Parameters |
| Scale | 0 – 5000PU |
| Imaging acquisition rate | Up to 120 FPS |
| Working distance | 10 – 35 cm |
| Image size | 1.57 × 1.57mm – 90 × 90mm |
| Image camera pixels | 4.2 million(2048 × 2048) |
| Max resolution | Up to 3μm/pixel |
| Zoom range | 12× optical zoom lens with auto-focus |
| Wavelength | 785nm |
Accessories
Citations
Using our laser speckle contrast imaging system for your reliable research, here are some references. Please contact us for reference lists on your chosen subject.
TBI:
Microvascular Injury in Mild Traumatic Brain Injury Accelerates Alzheimer-like Pathogenesis in Mice
Lower limb:
DW14006 as a direct AMPK activator ameliorates diabetic peripheral neuropathy in mice
Lymph and blood vessels:
Meningeal lymphatics clear erythrocytes that arise from subarachnoid hemorrhage
Ischemia model
14-3-3ζ-c-Src-integrin-β3 complex is vital for platelet activation
Diabetes and BBB:
Aging exacerbates impairments of cerebral blood flow autoregulation and cognition in diabetic rats
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