MT G2 MicroTester

Overview

• Compression, tension, bending, indentation
• Shear testing test modes when combined with the optional Shear Test Module
• Highest level precision using Piezo-electric actuators with 0.1µm resolution
• Optional second axis imaging
• Force resolution down to 10nN
• High resolution CCD imaging
• Integrated temperature-controlled media bath
• Fully featured user interface software for simple, cyclic, relaxation, and multi-modal testing with real-time feedback

The MicroTester is a micro-scale mechanical test system that does what others can’t. Smaller specimens, better force resolution, easier test setups, and great visuals. Applications include small tissue samples, hydrogel microspheres, cell spheroids, and engineered microtissues.

Videos

MicroScale Mechanical Testing Examples

Mechanical Testing of Soft Gels using the CellScale MicroSquisher

Muscle Tissue Construct Testing at Kent State University

CellScale MicroSquisher Instructional Overview

Compression Test of a Hydrogel Microsphere

Hydrogel Tension Test

  Zebrafish Embryo Cell Spheroid Compression Testing

 

Mechanical Testing of Soft Gels

 

Hydrogel MicroSphere Compression Test Demonstration

Specifications

	MTG2	MTLT
Dimensions	56 X 14 X 24cm	52 X 17 X 21cm
Weight	9kg	6.5kg
Force Capacity	500mN	500mN
Available Force Transducers	0.005, 0.02, 0.08, 0.2, 1, 5, 25, 100, 500mN	0.005, 0.02, 0.08, 0.2, 1, 5, 25, 100, 500mN
Force Accuracy	Approx. 0.2% of transducer capacity	Approx. 0.2% of transducer capacity
Maximum Grip Separation	Approx. 10mm	Approx. 10mm
Maximum Velocity	5mm/s	5mm/s
Maximum Cycle Frequency	0.5Hz	0.1Hz
Maximum Data Rate	15Hz	15Hz
Actuator Technology	Piezo-electric Motor	Stepper Motor
Actuator Resolution	0.1um	1um
Range of Field of View	0.4-11.0mm	0.8-5.5mm
Vertical Image Resolution	2048px	1536px
Secondary Camera Option	Yes	No
Secondary Test Axis Option (Shear)	Yes	No

Accessories

Citations

Dillon M. Brown, Machelle T. Pardue and C. Ross Ethier (2021). A biphasic approach for characterizing tensile, compressive and hydraulic properties of the sclera. Journal of the Royal Society, Interface vol. 18,174 (2021): 20200634. doi:10.1098/rsif.2020.0634

Yosuke Ida, Megumi Watanabe, Araya Umetsu, Hiroshi Ohguro, Fumihito Hikage, (2021). Addition of EP2 agonists to an FP agonist additively and synergistically modulates adipogenesis and the physical properties of 3D 3T3-L1 sphenoids. Prostaglandins, leukotrienes, and essential fatty acids vol. 171 (2021): 102315. doi:10.1016/j.plefa.2021.102315

Fumihito Hikage, Hanae Ichioka, Megumi Watanabe, Araya Umetsu, Hiroshi Ohguro & Yosuke Ida  (2021). Addition of ROCK inhibitors to prostaglandin derivative (PG) synergistically affects adipogenesis of the 3D spheroids of human orbital fibroblasts (HOFs). Human cell vol. 35,1 (2022): 125-132. doi:10.1007/s13577-021-00623-y

Babak N. Safa, Thomas Read,  Ross Ethier (2021). Assessment of the Viscoelastic Mechanical Properties of the Porcine Optic Nerve Head using Micromechanical Testing and Finite Element Modeling. Acta biomaterialia vol. 134 (2021): 379-387. doi:10.1016/j.actbio.2021.07.022

Watanabe, M.; Furuhashi, M.; Tsugeno, Y.; Ida, Y.; Hikage, F.; Ohguro, H. (2021). Autotaxin May Have Lysophosphatidic Acid-Unrelated Effects on Three-Dimension (3D) Cultured Human Trabecular Meshwork (HTM) Cells.  International journal of molecular sciences vol. 22,21 12039. 7 Nov. 2021, doi:10.3390/ijms222112039

Zheng Zhong, Alis Balayan, Jing Tian, Yi Xiang, Henry H Hwang, Xiaokang Wu, Xiaoqian Deng, Jacob Schimelman, Yazhi Sun, Chao Ma, Aurelie Dos Santos, Shangting You, Min Tang, Emmie Yao, Xiaoao Shi, Nicole F Steinmetz, Sophie X Deng and Shaochen Chen (2021). Bioprinting of dual ECM scaffolds encapsulating limbal stem/progenitor cells in active and quiescent statuses. Biofabrication vol. 13,4 10.1088/1758-5090/ac1992. 13 Aug. 2021, doi:10.1088/1758-5090/ac1992

Sophia Hauck, Paula Zager, Norbert Halfter, Elke Wandel, Marta Torregrossa, Ainur Kakpenova, Sandra Rother, Michelle Ordieres, Susann Räthel, Albrecht Berg, Stephanie Möller, Matthias Schnabelrauch, Jan C. Simon, Vera Hintze, Sandra Franz, (2021). Collagen/hyaluronan based hydrogels releasing sulfated hyaluronan improve dermal wound healing in diabetic mice via reducing inflammatory macrophage activity. Bioactive materials vol. 6,12 4342-4359. 30 Apr. 2021, doi:10.1016/j.bioactmat.2021.04.026

Michael Dattilo, Dillon Brown, C Ross Ethier (2021). Comparison of Optic Nerve Sheath Material Properties in male and female rhesus macaque. Invest. Ophthalmol. Vis. Sci. 2021;62(8):2677.

Sarah Al-Maawi, Sandra Rother, Norbert Halfter, Karen M. Fiebig, Juliane Moritz, Stephanie Moeller, Matthias Schnabelrauch, Charles James Kirkpatrick, Robert Sader, Hans-Peter Wiesmann, Dieter Scharnweber, Vera Hintze, Shahram Ghanaati, (2021). Covalent linkage of sulfated hyaluronan to the collagen scaffold Mucograft® enhances scaffold stability and reduces proinflammatory macrophage activation in vivo. Bioactive materials vol. 8 420-434. 22 Jun. 2021, doi:10.1016/j.bioactmat.2021.06.008

Andrea Acunaa, Julian M.Jimeneza, Naomi Denekeb, Sean M.Rothenbergera Sarah Libringa, Luis Solorioac, Vitaliy L.Rayza, Chelsea S.Davisb, Sarah Calve (2021). Design and validation of a modular micro-robotic system for the mechanical characterization of soft tissues. Acta biomaterialia vol. 134 (2021): 466-476. doi:10.1016/j.actbio.2021.07.035

Anna Kornmuller, Lauren E. Flynn (2021). Development and characterization of matrix-derived microcarriers from decellularized tissues using electrospraying techniques. Journal of biomedical materials research. Part A vol. 110,3 (2022): 559-575. doi:10.1002/jbm.a.37306

Bin Zhang, Alexander K. Nguyen, Roger J. Narayan, Jie Huang (2021). Direct ink writing of vancomycin-loaded polycaprolactone/ polyethylene oxide/ hydroxyapatite 3D scaffolds. J Am Ceram Soc. 2022; 105: 1821– 1840. https://doi.org/10.1111/jace.18048

Megumi Watanabe, Yosuke Ida, Hiroshi Ohguro, Chiaki Ota & Fumihito Hikage  (2021). Diverse effects of pan-ROCK and ROCK2 inhibitors on 2 D and 3D cultured human trabecular meshwork (HTM) cells treated with TGFβ2. Scientific reports vol. 11,1 15286. 27 Jul. 2021, doi:10.1038/s41598-021-94791-4

Ferdous B. Finklea, Yuan Tian, Petra Kerscher, Wen J. Seeto, Morgan E. Ellis, Elizabeth A. Lipke, (2021). Engineered cardiac tissue microsphere production through direct differentiation of hydrogel-encapsulated human pluripotent stem cells. Biomaterials vol. 274 (2021): 120818. doi:10.1016/j.biomaterials.2021.120818

T. Gonzalez-Fernandez, A. J. Tenorio, A. M. Saiz Jr, J. K. Leach (2021). Engineered Cell-Secreted Extracellular Matrix Modulates Cell Spheroid Mechanosensing and Amplifies their Response to Inductive Cues for the Formation of Mineralized Tissues. Advanced healthcare materials, e2102337. 30 Dec. 2021, doi:10.1002/adhm.202102337

Fazil E. Uslu, Christopher D. Davidson, Erik Mailand, Nikolaos Bouklas, Brendon M. Baker, Mahmut Selman Sakar (2021). Engineered Extracellular Matrices with Integrated Wireless Microactuators to Study Mechanobiology. Advanced materials (Deerfield Beach, Fla.) vol. 33,40 (2021): e2102641. doi:10.1002/adma.202102641

Watanabe, M., Ida, Y., Ohguro, H. et al. (2021). Establishment of appropriate glaucoma models using dexamethasone or TGFβ2 treated three-dimension (3D) cultured human trabecular meshwork (HTM) cells. Scientific reports vol. 11,1 19369. 29 Sep. 2021, doi:10.1038/s41598-021-98766-3

Shigeru Miyagawa, Takuji Kawamura, Emiko Ito, Maki Takeda, Hiroko Iseoka, Junya Yokoyama, Akima Harada, Noriko Mochizuki-Oda, Yukiko Imanishi-Ochi, Junjun Li, Masao Sasai, Fumiyo Kitaoka, Masaki Nomura, Naoki Amano, Tomoko Takahashi, Hiromi Dohi, Eiichi Morii, Yoshiki Sawa (2021). Evaluation of the Efficacy and Safety of a Clinical Grade Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Patch: A Pre-Clinical Study. 10.1101/2021.04.07.438744.

Mohammadi, M.R., Rodriguez, S.M., Luong, J.C. et al. (2021). Exosome loaded immunomodulatory biomaterials alleviate local immune response in immunocompetent diabetic mice post islet xenotransplantation. Communications biology vol. 4,1 685. 3 Jun. 2021, doi:10.1038/s42003-021-02229-4

Chun Liu, Miao Li, Zhao-Xia Dong, Dong Jiang, Xiaojing Li, Shuibin Lin, Demeng Chen, Xuenong Zou, Xing-Ding Zhang, Gary D. Luker, (2021). Heterogeneous microenvironmental stiffness regulates pro-metastatic functions of breast cancer cells. Acta biomaterialia vol. 131 (2021): 326-340. doi:10.1016/j.actbio.2021.07.009

Ying Lei, Luciano Bortolin, Frank Benesch-Lee, Teniola Oguntolu, Zhijie Dong, Narda Bondah, Kristen Billiar, (2021). Hyaluronic acid regulates heart valve interstitial cell contraction in fibrin-based scaffolds. Acta biomaterialia vol. 136 (2021): 124-136. doi:10.1016/j.actbio.2021.09.046

Elizaveta V. Koudan, Mikhail N. Zharkov, Mikhail V. Gerasimov, Saida Sh. Karshieva, Aleksandra D. Shirshova, Vladimir V. Chrishtop, Vladimir A. Kasyanov, Aleksandr A. Levin, Vladislav A. Parfenov, Pavel A. Karalkin, Frederico D. A. S. Pereira, Stanislav V. Petrov, Nikolay A. Pyataev, Yusef D. Khesuani, Vladimir A. Mironov, and Gleb B. Sukhorukov (2021). Magnetic Patterning of Tissue Spheroids Using Polymer Microcapsules Containing Iron Oxide Nanoparticles. ACS biomaterials science & engineering vol. 7,11 (2021): 5206-5214. doi:10.1021/acsbiomaterials.1c00805

Christopher D. Davidson,  Samuel J. DePalma,  William Y. Wang, Jordan L. Kamen, Danica Kristen P. Jayco,  Brendon M. Baker (2021). Mechanical intercellular communication via matrix-borne cell force transmission during vascular network formation. bioRxiv 2021.08.17.456669; doi: https://doi.org/10.1101/2021.08.17.456669

Manuel Alejandro Tamargo, Trevor Ray Nash, Sharon Fleischer, Youngbin Kim, Olaia Fernandez Vila, Keith Yeager, Max Summers, Yimu Zhao, Roberta Lock, Miguel Chavez, Troy Costa, and Gordana Vunjak-Novakovic (2021). milliPillar: A Platform for the Generation and Real-Time Assessment of Human Engineered Cardiac Tissues. ACS biomaterials science & engineering vol. 7,11 (2021): 5215-5229. doi:10.1021/acsbiomaterials.1c01006

Pascal Morissette Martin, John T. Walker, Kellie J. Kim, Courtney R. Brooks, Fiona E. Serack, Anna Kornmuller, Laura Juignet, Amanda M. Hamilton, P. Joy Dunmore-Buyze, Maria Drangova, John A. Ronald, Lauren E. Flynn, (2021). Modular cell-assembled adipose matrix-derived bead foams as a mesenchymal stromal cell delivery platform for soft tissue regeneration. Biomaterials vol. 275 (2021): 120978. doi:10.1016/j.biomaterials.2021.120978

Kevin J. De France, Fei Xu, Samaneh Toufanian, Katelyn J.W. Chan, Somiraa Said, Taylor C. Stimpson, Eduardo González-Martínez, Jose M. Moran-Mirabal, Emily D. Cranston, Todd Hoare (2021). Multi-scale structuring of cell-instructive cellulose nanocrystal composite hydrogel sheets via sequential electrospinning and thermal wrinkling. Acta biomaterialia vol. 128 (2021): 250-261. doi:10.1016/j.actbio.2021.04.044

Frank P. Assen, Miroslav Hons, Robert Hauschild, Shayan Shamipour, Jun Abe, Walter A. Kaufmann, Tommaso Costanzo, Gabriel Krens, Markus Brown, Burkhard Ludewig, Simon Hippenmeyer, Jens V. Stein, Carl-Philipp Heisenberg, Edouard Hannezo, Sanjiv A. Luther, Michael Sixt (2021). Multi-tier mechanics control stromal adaptations in swelling lymph nodes. bioRxiv 2021.07.28.454217; doi: https://doi.org/10.1101/2021.07.28.454217

Anna Gryadunova, Jesil Kasamkattil, Max Hans Peter Gay, Boris Dasen, Karoliina Pelttari, Vladimir Mironov, Ivan Martin, Stefan Schären, Andrea Barbero, Olga Krupkova, Arne Mehrkens (2021). Nose to Spine: spheroids generated by human nasal chondrocytes for scaffold-free nucleus pulposus augmentation. Acta biomaterialia vol. 134 (2021): 240-251. doi:10.1016/j.actbio.2021.07.064

Yanbarisov R., Efremo Y., Kosheleva N., Timashev P., Vassilevski Y.  (2021). Numerical Modelling of Multicellular Spheroid Compression: Viscoelastic Fluid vs. Viscoelastic Solid Mathematics 9, no. 18: 2333. https://doi.org/10.3390/math9182333

Watanabe M., Ida Y., Furuhashi M., Tsugeno Y., Hikage F., Ohguro, H. (2021). Pan-ROCK and ROCK2 Inhibitors Affect Dexamethasone-Treated 2D- and 3D-Cultured Human Trabecular Meshwork (HTM) Cells in Opposite Manners. Molecules (Basel, Switzerland) vol. 26,21 6382. 22 Oct. 2021, doi:10.3390/molecules26216382

Mikio Shiba, Shuichiro Higo, Takumi Kondo, Junjun Li, Li Liu, Yoshihiko Ikeda, Yasuaki Kohama, Satoshi Kameda, Tomoka Tabata, Hiroyuki Inoue, Satoki Nakamura, Maki Takeda, Emiko Ito, Seiji Takashima, Shigeru Miyagawa, Yoshiki Sawa, Shungo Hikoso, Yasushi Sakata (2021). Phenotypic recapitulation and correction of desmoglein-2-deficient cardiomyopathy using human-induced pluripotent stem cell-derived cardiomyocytes . Human molecular genetics vol. 30,15 (2021): 1384-1397. doi:10.1093/hmg/ddab127

Jong Hyun Kim, Jong Bin Kim, Ye Hun Choi, Sanghyuk Park, Shin-Hyun Kim (2021). Photonic Microbeads Templated by Oil-in-Oil Emulsion Droplets for High Saturation of Structural Colors. Small (Weinheim an der Bergstrasse, Germany), e2105225. 10 Dec. 2021, doi:10.1002/smll.202105225

Ida Y., Furuhashi M., Watanabe, M., Umetsu A., Hikage F., Ohguro H. (2021). Prostaglandin F2 and EP2 Agonists Exert Different Effects on 3D 3T3-L1 Spheroids during Their Culture Phase. Biomedicines vol. 9,12 1821. 2 Dec. 2021, doi:10.3390/biomedicines9121821

Kaku Itoh, Yosuke Ida, Hiroshi Ohguro & Fumihito Hikage  (2021). Prostaglandin F2α agonists induced enhancement in collagen1 expression is involved in the pathogenesis of the deepening of upper eyelid sulcus. Scientific reports vol. 11,1 9002. 26 Apr. 2021, doi:10.1038/s41598-021-88562-4

Hanae Ichioka, Yosuke Ida, Megumi Watanabe, Hiroshi Ohguro, Fumihito Hikage, (2021). Prostaglandin F2α and EP2 agonists, and a ROCK inhibitor modulate the formation of 3D organoids of Grave's orbitopathy related human orbital fibroblasts. Experimental eye research vol. 205 (2021): 108489. doi:10.1016/j.exer.2021.108489

Min Tang, Shashi Kant Tiwari, Kriti Agrawal, Matthew Tan, Jason Dang, Trevor Tam, Jing Tian, Xueyi Wan, Jacob Schimelman, Shangting You, Qinghui Xia, Tariq M. Rana, Shaochen Chen (2021). Rapid 3D Bioprinting of Glioblastoma Model Mimicking Native Biophysical Heterogeneity. Small (Weinheim an der Bergstrasse, Germany) vol. 17,15 (2021): e2006050. doi:10.1002/smll.202006050

Ida Y., Ichioka H., Furuhashi M., Hikage F., Watanabe M., Umetsu A., Ohguro H. (2021). Reactivities of a Prostanoid EP2 Agonist, Omidenepag, Are Useful for Distinguishing between 3D Spheroids of Human Orbital Fibroblasts without or with Graves’ Orbitopathy. Cells vol. 10,11 3196. 16 Nov. 2021, doi:10.3390/cells10113196

Ida Y., Hikage F. & Ohguro, H. (2021). ROCK inhibitors enhance the production of large lipid-enriched 3D organoids of 3T3-L1 cells. Scientific reports vol. 11,1 5479. 9 Mar. 2021, doi:10.1038/s41598-021-84955-7

Fumihito Hikage, Hanae Ichioka, Megumi Watanabe, Araya Umetsu, Hiroshi Ohguro, Yosuke Ida (2021). ROCK inhibitors modulate the physical properties and adipogenesis of 3D spheroids of human orbital fibroblasts in different manners. FASEB bioAdvances vol. 3,10 866-872. 26 Jul. 2021, doi:10.1096/fba.2021-00037

Oouchi  Y., Watanabe M., Ida Y., Ohguro H., Hikage F.  (2021). Rosiglitasone and ROCK Inhibitors Modulate Fibrogenetic Changes in TGF-β2 Treated Human Conjunctival Fibroblasts (HconF) in Different Manners. International journal of molecular sciences vol. 22,14 7335. 8 Jul. 2021, doi:10.3390/ijms22147335

Watanabe M, Ida Y, Furuhashi M, Tsugeno Y, Ohguro H, Hikage F.  (2021). Screening of the Drug-Induced Effects of Prostaglandin EP2 and FP Agonists on 3D Cultures of Dexamethasone-Treated Human Trabecular Meshwork Cells. Biomedicines vol. 9,8 930. 31 Jul. 2021, doi:10.3390/biomedicines9080930

Ida Y., Watanabe M., Ohguro H., Hikage F. (2021). Simultaneous Use of ROCK Inhibitors and EP2 Agonists Induces Unexpected Effects on Adipogenesis and the Physical Properties of 3T3-L1 Preadipocytes. International journal of molecular sciences vol. 22,9 4648. 28 Apr. 2021, doi:10.3390/ijms22094648

So Hyun Ahn, Medha Rath, Chen-Yu Tsao, William E. Bentley, and Srinivasa R. Raghavan (2021). Single-Step Synthesis of Alginate Microgels Enveloped with a Covalent Polymeric Shell: A Simple Way to Protect Encapsulated Cells. International journal of molecular sciences vol. 22,9 4648. 28 Apr. 2021, doi:10.3390/ijms22094648

Yosuke Ida, Araya Umetsu, Masato Furuhashi, Megumi Watanabe, Fumihito Hikage, Hiroshi Ohguro (2021). The EP2 agonist, omidenepag, alters the physical stiffness of 3D spheroids prepared from human corneal stroma fibroblasts differently depending on the osmotic pressure. FASEB journal : official publication of the Federation of American Societies for Experimental Biology vol. 36,1 (2022): e22067. doi:10.1096/fj.202101263R

Gabriela S. Kronemberger, Anderson Beatrici, Gisele M. L. Dalmônico, André L. Rossi, Guilherme A. S. C. Miranda, Leonardo C. Boldrini, José Mauro Granjeiro, Leandra Santos Baptista (2021). The hypertrophic cartilage induction influences the building-block capacity of human adipose stem/stromal cell spheroids for biofabrication. Artificial organs vol. 45,10 (2021): 1208-1218. doi:10.1111/aor.14000

Afshar, M.E., Abraha, H.Y., Bakooshli, M.A., Davoudi, S., Thavandiran, N., Tung, K., Ahn, H., Ginsberg, H.J., Zandstra, P.W. and Gilbert, P.M. (2020).  A 96-well culture platform enables longitudinal analyses of engineered human skeletal muscle microtissue strength. Scientific reports vol. 10,1 6918. 24 Apr. 2020, doi:10.1038/s41598-020-62837-8

Brown, D.M., Pardue, M.T. and Ethier, C.R. (2020). A Biphasic Approach for Characterizing Tensile, Compressive, and Hydraulic Properties of the Sclera. Journal of the Royal Society, Interface vol. 18,174 (2021): 20200634. doi:10.1098/rsif.2020.0634

Park, H., Collignon, A.M., Lepry, W.C., Ramirez-GarciaLuna, J.L., Rosenzweig, D.H., Chaussain, C. and Nazhat, S.N. (2020). Acellular dense collagen-S53P4 bioactive glass hybrid gel scaffolds form more bone than stem cell delivered constructs. Materials science & engineering. C, Materials for biological applications vol. 120 (2021): 111743. doi:10.1016/j.msec.2020.111743

Wang, S., Maruri, D.P., Boothby, J.M., Lu, X., Rivera-Tarazona, L.K., Varner, V.D. and Ware, T.H. (2020). Anisotropic, porous hydrogels templated by lyotropic chromonic liquid crystals. Journal of materials chemistry. B vol. 8,31 (2020): 6988-6998. doi:10.1039/d0tb00904k

D. Wangpraseurt, S. You, F. Azam, G. Jacucci, O. Gaidarenko, M. Hildebrand, M. Kuhl, A. Smith, M. Davey, A. Smith, D. Deheyn, S. Chen, S. Vignolini (2020). Bionic 3D Printed Corals. Nature communications vol. 11,1 1748. 9 Apr. 2020, doi:10.1038/s41467-020-15486-4

Tang, C., Brodie, P., Brunsting, M. and Tam, K.C. (2020). Carboxylated Cellulose Cryogel Beads via a One-step Ester Crosslinking of Maleic Anhydride for Copper Ions Removal. Carbohydrate polymers vol. 242 (2020): 116397. doi:10.1016/j.carbpol.2020.116397

Kosheleva, N.V., Efremov, Y.M., Shavkuta, B.S., Zurina, I.M., Zhang, D., Zhang, Y., Minaev, N.V., Gorkun, A.A., Wei, S., Shpichka, A.A. and Saburina, I.N. (2020). Cell spheroid fusion: beyond liquid drops model. Scientific reports vol. 10,1 12614. 28 Jul. 2020, doi:10.1038/s41598-020-69540-8

Li, J., Zhang, L., Yu, L., Minami, I., Miyagawa, S., Hörning, M., Dong, J., Qiao, J., Qu, X., Hua, Y. and Fujimoto, N. (2020). Circulating re-entrant waves promote maturation of hiPSC-derived cardiomyocytes in self-organized tissue ring. Communications biology vol. 3,1 122. 13 Mar. 2020, doi:10.1038/s42003-020-0853-0

Gryadunova, A.A., Koudan, E.V., Rodionov, S.A., Pereira, F.D.A.S., Meteleva, N.Y., Kasyanov, V.A., Parfenov, V.A., Kovalev, A.V., Khesuani, Y.D., Mironov, V.A. and Bulanova, E.A. (2020). Cytoskeleton systems contribute differently to the functional intrinsic properties of chondrospheres. Acta biomaterialia vol. 118 (2020): 141-152. doi:10.1016/j.actbio.2020.10.007

Rihani, R.T., Stiller, A.M., Usoro, J.O., Lawson, J., Kim, H., Black, B.J., Danda, V.R., Maeng, J., Varner, V.D., Ware, T.H. and Pancrazio, J.J. (2020). Deployable, liquid crystal elastomer-based intracortical probes. Acta biomaterialia vol. 111 (2020): 54-64. doi:10.1016/j.actbio.2020.04.032

M. Ruoß, S. Rebholz, M. Weimer, C. Grom-Baumgarten, K. Anthanasopulu, R. Kemkemer, H. Käß, S. Ehnert, A. Nussler (2020). Development of Scaffolds with Adjusted Stiffness for Mimicking Disease-Related Alterations of Liver Rigidity. Journal of functional biomaterials vol. 11,1 17. 14 Mar. 2020, doi:10.3390/jfb11010017

Liu, J., Miller, K., Ma, X., Dewan, S., Lawrence, N., Whang, G., Chung, P., McCulloch, A.D. and Chen, S. (2020). Direct 3D bioprinting of cardiac micro-tissues mimicking native myocardium. Biomaterials vol. 256 (2020): 120204. doi:10.1016/j.biomaterials.2020.120204

Itoh, K., Ida, Y., Ohguro, H. and Hikage, F. (2020). Enhancement of collagen 1 expression by prostaglandin F2α agonists is pivotally involved in the pathogenesis of deepening of the upper eyelid sulcus. Scientific reports vol. 11,1 9002. 26 Apr. 2021, doi:10.1038/s41598-021-88562-4

Dattilo, Michael, Dillon Brown, and C. Ross Ethier. (2020). Experimental measurement of optic nerve sheath material properties.

Davidson, C.D., Jayco, D.K.P., Wang, W.Y., Shikanov, A. and Baker, B.M. (2020). Fiber Crimp Confers Matrix Mechanical Nonlinearity, Regulates Endothelial Cell Mechanosensing, and Promotes Microvascular Network Formation. Journal of biomechanical engineering vol. 142,11 (2020): 111009. doi:10.1115/1.4048191

Kulwatno, J., Gearhart, J., Gong, X., Herzog, N., Getzin, M., Skobe, M. and Mills, K.L. (2020). Growth of tumor emboli within a vessel model reveals dependence on the magnitude of mechanical constraint. Integrative biology : quantitative biosciences from nano to macro vol. 13,1 (2021): 1-16. doi:10.1093/intbio/zyaa024

H. Hwang, S. You, X. Ma, L. Kwe, G. Victorine, N. Lawrence, X. Wan, H. Shen, W. Zhu, S. Chen (2020). High throughput direct 3D bioprinting in multiwell plates. Biofabrication, 10.1088/1758-5090/ab89ca. 16 Apr. 2020, doi:10.1088/1758-5090/ab89ca

Schmitt, T., Kajave, N., Cai, H.H., Gu, L., Albanna, M. and Kishore, V. (2020). In vitro characterization of xeno-free clinically relevant human collagen and its applicability in cell-laden 3D bioprinting. Journal of biomaterials applications vol. 35,8 (2021): 912-923. doi:10.1177/0885328220959162

Parfenov, V.A., Khesuani, Y.D., Petrov, S.V., Karalkin, P.A., Koudan, E.V., Nezhurina, E.K., Pereira, F.D., Krokhmal, A.A., Gryadunova, A.A., Bulanova, E.A. and Vakhrushev, I.V. (2020). Magnetic levitational bioassembly of 3D tissue construct in space. Science advances vol. 6,29 eaba4174. 15 Jul. 2020, doi:10.1126/sciadv.aba4174

DePalma, S.J., Davidson, C.D., Stis, A.E., Helms, A.S. and Baker, B. (2020). Microenvironmental determinants of organized iPSC-cardiomyocyte tissues on synthetic fibrous matrices.  Biomaterials science vol. 9,1 (2021): 93-107. doi:10.1039/d0bm01247e

E. Koudan, A. Gryadunova, P. Karalkin, J. Korneva, N. Meteleva, I. Babichenko, A. Volkov, S. Rodionov, V. Parfenov, F. Pereira, Y. Khesuani, V. Mironov, E. Bulanova (2020). Multiparametric Analysis of Tissue Spheroids Fabricated from Different Types of Cells. Biotechnology journal vol. 15,5 (2020): e1900217. doi:10.1002/biot.201900217

C. Davidson, D. Jayco, D. Matera, S. DePalma, H. Hiraki, W. Wang, B. Baker (2020). Myofibroblast activation in synthetic fibrous matrices composed of dextran vinyl sulfone. Acta biomaterialia vol. 105 (2020): 78-86. doi:10.1016/j.actbio.2020.01.009

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